Table 3.
Stress perfusion CMR (summary studies)
Study | n | CAD Prevalence (%) | Sensitivity (%) | Specificity (%) | PPV | NPV |
---|---|---|---|---|---|---|
Nagel et al67 | 84 | 51 | 88 | 90 | 90 | 90 |
Ishida et al68 | 104 | 74 | 90 | 85 | 95 | 74 |
Doyle et al69,¶ | 184 | 14 | 57 | 78 | 30 | 92 |
Plein et al 22,§ | 68 | 82 | 88 | 83 | 96 | 59 |
Takase et al70 | 102 | 74 | 93 | 85 | 95 | 81 |
Giang et al65,† | 80 | 65 | 93 | 75 | 87 | 86 |
Plein et al71 | 92 | 72 | 88 | 82 | 90 | 79 |
Klem et al59 | 92 | 40 | 89 | 87 | 83 | 92 |
Pilz et al72 | 171 | 66 | 96 | 83 | 92 | 92 |
Merkle et al73 | 228 | 75 | 93 | 86 | 95 | 80 |
Schwitter et al74,† | 225 | 77 | 85 | 67 | 89 | 58 |
Gebker et al75 | 101 | 69 | 90 | 71 | 88 | 76 |
Klem et al76,†,‡ | 136 | 27 | 84 | 88 | 72 | 94 |
Thomas et al77,║ | 60 | 47 | 93 | 84 | 84 | 93 |
Meta-analysis | ||||||
Nandalur et al46 | 1183 | 57.4 | 91 | 81 | 87 | 87 |
Hamon et al78 | 2125 | 57 | 89 | 80 | 85 | 85 |
Abbreviations: CAD, coronary artery disease; NPV, negative predictive value; PPV, positive predictive value.
Multicenter studies.
Study population, women only.
Patients presenting to ED with suspected ACS.
3.0 T and myocardial tagging.
Study population, women only Women’s Ischemia Syndrome Evaluation (WISE) study. Myocardial flow reserve index was used to assess for ischemia.