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. Author manuscript; available in PMC: 2014 Mar 14.
Published in final edited form as: Heart Fail Rev. 2011 Jul;16(4):381–395. doi: 10.1007/s10741-010-9201-7

Table 1.

Techniques to study myocardial viability

Technique Imaging finding Criteria for viability
Echocardiography
Left ventricular wall thickness
Inotropic contractile reserve
>6 mm [9]
Biphasic response better predictive accuracy versus monophasic response [14]
Contrast echocardiography perfusion imaging
Strain and strain rate imaging
No perfusion defect [16]
Global left ventricular strain of −13.7% on automated function imaging [13]
Cardiac MRI
Left ventricular wall thickness
Inotropic contractile reserve
LGE
>5.5 mm [22]
Improved contractility [22]
<25% transmural LGE
26–50% transmural LGE intermediate recovery [31]
Radionuclide techniques
SPECT
 Thallium-201 Perfusion
Redistribution
>50% peak levels [38, 39]
>50% peak levels [38, 39]
 Technetium-99m Perfusion >50% peak levels [39]
 Nitrate-enhanced perfusion imaging Perfusion >50% peak levels [36]
 Low-dose dobutamine Contractile reserve Improvement in regional wall motion with low-dose dobutamine [38]
PET
 F-18 FDG Glucose uptake >50% peak activity

LGE late gadolinium enhancement

The techniques of strain and strain rate imaging, 3D echocardiography, BMIPP SPECT, C-11 acetate and palmitate PET, and delayed contrast enhancement using MDCT are currently under investigation and criteria for viability are not well established