Table I.
Maternal characteristics and pregnancy outcomes |
ART (N=273) |
PMTCT (N=74) |
p-value ART v. PMTCT |
No intervention (N=29) |
p-value ART v. no intervention |
---|---|---|---|---|---|
Age | 27.8 (25–31) | 27 (23–32) | 0.547 | 24.5 (23.5–28.5) | 0.02 |
WHO stage I and II | 179 (79%) | 55 (74%) | 0.146 | 15 (52%) | 0.296 |
III | 78 (34%) | 16 (23%) | 13 (45%) | ||
IV | 8 (3%) | 2 (3%) | 0 | ||
Unknown | 0 | 0 | 1 (3%) | ||
TB at enrolment | 23 (8%) | 5 (7%) | 0.425 | 7 (24%) | 0.015 |
Gestation at enrolment | 27 (22–31) | 32 (29–34) | <0.001 | 26 (22–30) | 0.878 |
CD4 at baseline | 127 (84–168) (N=268) |
166 (128–267) (N=67) |
<0.001 | 153 (75–247) (N=24) |
0.109 |
Viral load at baseline | 30 721 (2 762–50 545) (N=267) |
17 794 (2 762–50 545) (N=67) |
0.013 | 40 812 (14 969–91 870) (N=24) |
0.262 |
Gestation at birth | 38.3 (36–40) (N=252) |
36 (34–38) (N=30) |
0.002 | 34 (27–39) (N=8) |
0.028 |
Live birth | 241 (88%) | 31 (42%) | <0.001 (live v. stillbirth, p=0.568) |
7 (24%) | <0.001 (live v. stillbirths, p=0.004) |
Stillbirth/miscarriage | 14 (5%) | 2 (3%) | 4 (14%) | ||
Termination/abortion | 4 (2%) | 0 | 0 | ||
Unknown | 14 (5%) | 41 (55%) | 18 (62%) | ||
Of live births: | |||||
HIV-negative | 203 (84%) | 23 (74%) | 0.067 (excluding unknowns, p=0.317) |
3 (43%) | 0.011 (excluding unknowns, p=0.855) |
HIV-positive | 11 (5%) | 0 | 0 | ||
HIV status unknown | 27 (11%) | 8 (26%) | 4 (57%) | ||
VL<400 at first follow-up | 203 (74%) | ||||
400<10 000 | 10 (4%) | ||||
>10 000 | 20 (7%) | ||||
Unknown | 40 (15%) | ||||
Days after start | 115 (112–124) | ||||
CD4 at first follow-up | 257 (165–335) (N=233) |
||||
Days after start | 115 (112–124) |
For continuous variables, data represent medians (interquartile range).