Table II.
Maternal characteristics and pregnancy outcomes |
HIV-negative infants (N=206) |
HIV-positive infants (N=11) |
p -value HIV-negative v. HIV-positive |
Infants unknown HIV status (N=24) |
p-value HIV- negative v. unknown |
---|---|---|---|---|---|
Age | 28.2 (25–32) | 26.5 (22–30) | 0.138 | 24 (25–28) | 0.018 |
WHO stage I and II | 145 (70%) | 3 (27%) | 0.01 | 23 (85%) | 0.637 |
III | 55 (27%) | 6 (55%) | 4 (15%) | ||
IV | 6 (3%) | 2 (18%) | 0 | ||
TB at enrolment | 15 (7%) | 2 (18%) | 0.214 | 1 (4%) | 0.416 |
Gestation at enrolment | 27 (23–31) (N=205) |
32 (28–34) (N=11) |
0.036 | 27 (23–31) (N=24) |
0.835 |
CD4 at baseline | 125 (81–164) (N=202) |
174 (118–193) (N=11) |
0.063 | 144 (78–186) (N=23) |
0.18 |
VL at baseline | 29 537 (8 969–75 758) (N=199) |
32 086 (14 409–67 656) (N=11) |
0.746 | 13 250 (1 800–40 176) (N=23) |
0.024 |
Weeks on ART (median) | 7.6 (4–12) | 4.7 (2.7–7.6) | 0.029 | 8 (5–12) | 0.684 |
Gestation at birth | 38 (36–40) (N=201) |
40 (37–41) (N=11) |
0.33 | 39 (38–41) (N=13) |
0.241 |
Delivery mode: NVD | 68 (33%) | 2 (27%) | 9 (37%) | ||
Caesarean | 54 (26%) | 3 (18%) | 0.43 | 6 (6%) | 0.488 |
Unknown | 85 (41%) | 6 (55%) | 10 (41%) | ||
First follow-up viral load | <50 (0) (N=192) |
54 (49–791) (N=11) |
0.018 | 49 (0) (N=15) |
0.387 |
Start to follow-up VL (days) | 115 (112–123) | 129 (112–158) | 0.777 | 112 (112–116) | 0.271 |
<400 at first follow-up | 169 (82%) | 8 (73%) | 14 (58%) | ||
400<10 000 | 7 (3%) | 1 (9%) | 0.235 | 0 | 1 |
>10 000 | 16 (8%) | 2 (18%) | 1 (4%) | ||
Unknown | 11 (5%) | 0 | 10 (42%) | ||
CD4 at first follow-up | 248 (162–327) (N=196) |
337 (182–455) (N=11) |
0.207 | 247 (160–299) (N=15) |
0.869 |
Start to follow-up CD4 (days) | 115 (112–123) | 119 (111–194) | 0.584 | 112 (112–116) | 0.384 |
Breastfeeding | 6 (3%) | 0 | 0.722 | 1 (4%) | 0.312 |
Not breastfeeding | 122 (58%) | 7 (64%) | 6 (26%) | ||
Median age at PCR (days) | 93 (75–124) (N=122) |
87 (70–93) (N=7) |
For continuous variables, data represent medians (interquartile range).