Skip to main content
. 2014 Mar 14;9(3):e91512. doi: 10.1371/journal.pone.0091512

Figure 5. Reactions of Parv+ and Cr+ interneurons to QA.

Figure 5

The Parv+ interneurons were mainly distributed in the dorsolateral striatum in the control group (A and A′). These interneurons in the QA group (B and B′) were extremely scarce in the lesion core (★) and presented some changes in the transition zone (*) including decrease in neuron number and increase in the number of varicosities which formed along the neuronal processes (see the arrow in B′ and the view of higher magnification in B*), but hyperplasia of fibers was not obvious. The Cr+ interneurons were mainly distributed in the medial striatum in the control rats (C and C′). In the QA group (D and D′), this interneuron type hardly survived in the lesion core but the neuron number was not notably reduced in the transition zone. However, the Cr+ interneurons reacted to QA by remarkably proliferating fibers and forming varicosities (see the arrow in D′ and the view of higher magnification in D*). Panels A′–D′ are views of higher magnification from the boxes of Panels A–D, respectively. Cont is short for control. Scale bars: A–D, 100 μm; A′–D′, 30 μm; B* and D*, 10 μm.