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. Author manuscript; available in PMC: 2015 Jan 15.
Published in final edited form as: Bioorg Med Chem Lett. 2013 Dec 9;24(2):601–603. doi: 10.1016/j.bmcl.2013.12.013

Table 1.

5-((1-benzyl-1H-indol-3-yl)methylene)-1,3-dimethyl-pyrimidine-2,4,6(1H,3H,5H)-trione analogs (3a– 3i)

Compound R1 R2
3a COOCH3 p-SO2Ph
3b H o-Br
3c H p-CH3
3d H p-OCH3
3e H p-CN
3f H p-Cl
3g H p-F
3h Cl p-F
3i COOCH3 p-COOCH3

If (ODtest - ODtzero) ≥ 0, then PG = 100 × (ODtest - ODtzero)/(ODctrl - ODtzero) and percentage growth is shown as positive.

If (ODtest - ODtzero) < 0, then PG = 100 × (ODtest - ODtzero)/ODtzero and percentage growth is shown as negative, which implies cell death.15