Skip to main content
. 2014 Mar 14;9(3):e91179. doi: 10.1371/journal.pone.0091179

Table 2. Degree of representation of the three transgenic zebrafish liver cancer signatures in human HCCs.

GEO accession xmrk kras Myc Total* xmrk/kras xmrk/Myc kras/Myc xmrk/kras/Myc
A GSE364 12.6% 17.2% 19.5% 31.0% 8.0% 6.9% 6.9% 3.4%
B GSE1898 9.9% 11.0% 16.5% 22.0% 8.8% 7.7% 7.7% 6.6%
C GSE10141 28.8% 25.0% 17.5% 46.3% 16.3% 7.5% 5.0% 3.8%
D GSE9843 35.2% 23.1% 25.3% 54.9% 14.3% 9.9% 8.8% 4.4%
E GSE19977 37.8% 21.3% 25.0% 45.1% 20.1% 18.9% 13.4% 13.4%
F GSE10186 32.2% 27.1% 12.7% 44.9% 19.5% 5.1% 6.8% 4.2%
G GSE20017 44.4% 23.7% 30.4% 50.4% 23.0% 24.4% 17.8% 17.0%
H GSE25097 34.7% 31.0% 34.7% 60.4% 20.1% 14.9% 15.3% 10.4%
I GSE5975 26.9% 32.4% 32.4% 46.2% 22.3% 17.2% 21.4% 15.5%
J GSE14520 30.5% 20.0% 20.5% 47.6% 11.4% 10.0% 6.2% 3.3%
Total 29.2% 23.5% 23.8% 47.2% 16.9% 12.5% 11.5% 8.8%

Percentages indicate the percentages of human HCC samples which showed significant positive correlation (FDR<0.25) with the zebrafish liver cancer signatures.

*Total: The total percentage of human HCCs which showed significant correlation with any one or more of the zebrafish signatures.