Scheme 1.
Synthesis of amidine analogs of triazolothienopyrimidine lead structure 1c. Reagents and conditions: (a) described previously;12 (b) 1° amines, PyBOP, CH3CN, DBU, microwave irradiation, 100 °C, 30 min.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.