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. 2014 Mar 14;9(3):e91848. doi: 10.1371/journal.pone.0091848

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© 2014 Alaimo et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Mn induced damage into rat striatal tissue (A). Rats were injected into the striatum with 1 µmol Mn (left) and saline solution (right), as indicated with dotted lines. Nissl staining on vibratome brain sections containing striatum from Mn-treated (a,b) and control (c,d) rats (B). Magnification: 10X (a,c) and 40X (b,d); Nuclei staining (C). Arrowheads: cells with shrunken shape and pyknotic nuclei. Magnification: 100X. Samples correspond to sections from rats receiving a single striatum injection of Mn and euthanized 7 days after. Scale bar: 10 µm.