Table 2. Frequency of selected comorbid causes of death and odds ratios (95% CI) comparing NTM-related mortality with tuberculosis-related mortality, United States, 1999–2010.
| Comorbid condition | NTM (Total number: 2990) | Tuberculosis (Total number: 8159) | P value- OR** (95%CI) | ||
| Frequency ofcomorbidconditions (%) | Age-adjustedmortalityrate (CI 95%) | Frequency ofcomorbid condition(%) | Age-adjustedmortalityrate (95% CI)* | ||
| COPD | 719 (24) | 0.02 (0.02–0.02) | 924 (11) | 0.02 (0.02–0.02) | <0.01, 2.5 (2.2–2.8) |
| Chronic respiratory failure | 39 (1) | TL*** | 47 (0.6) | TL | <0.01, 2.3 (1.5–3.5) |
| Mental and behavioraldisorder due touse tobacco | 293 (10) | TL | 373 (5) | 0.01 (0.001–0.01) | <0.01, 2.3 (1.9–2.7) |
| Mental and behavioraldisorder due touse alcohol | 15 (0.5) | UR$ | 117 (1.4) | TL | <0.01, 0.35 (0.2–0.6) |
| Bronchiectasis | 244 (8) | 0.01 (0.01–0.01) | 192 (2) | 0.01 (0.001–0.01) | <0.01, 3.7 (3–4.5) |
| HIV | 14 (0.5) | UR | 5 (0.1) | UR | <0.01, 7.7 (2.8–21.3) |
| Chronic renal failure | 43 (1) | TL | 242 (3) | TL | <0.01, 0.5 (0.3–0.7) |
| Liver disease | 17 (0.6) | UR | 148 (2) | NA | <0.01, 0.3 (0.2–0.5) |
| Diabetes Mellitus | 102 (3) | TL | 596 (7) | 0.01 (0.01–0.01) | <0.01, 0.5 (0.4–0.6) |
| Interstitial lung diseases | 196 (7) | 0.01 (0.01–0.01) | 336 (4) | 0.01 (0.01–0.01) | <0.01, 1.6 (1.4–2) |
| Rheumatoid arthritis | 51 (2) | TL | 83 (1) | TL | <0.01, 1.7 (1.2–2.4) |
| Primary immunodeficiency | 63 (2) | TL | 44 (0.5) | TL | <0.01, 4 (2.7–5.9) |
| Lymphoma andhematopoieticmalignancies | 32 (1.1) | TL | 45 (0.6) | TL | <0.01, 2 (1.2–3) |
* 95% CIs: 95% Confidence intervals, **OR: Odds ratio, ***TL: Too low when OR and 95% CI calculated as 0.001(0.001–0.001), $UR: Unreliable.