Table 2. IC50 values of studied Cyclopia sp. extracts, calculated with RTCA.
Cyclopia sp. extract | HeLa IC50 and R2 | HaCaT IC50 and R2 |
C | 1.458 μg/ml; R2 = 0.946 | 6.76 μg/ml; R2 = 0.921 |
D | 13.30 μg/ml; R2 = 0.978 | 18.45 μg/ml; R2 = 0.937 |
E | 1.667 μg/m; R2 = 0.981 | 5.26 μg/m; R2 = 0.9876 |
F | 10.60 μg/ml; R2 = 0.993 | 17.38 μg/ml; R2 = 0.945 |
IC50 values were calculated in RTCA software, with use of non-linear regression (sigmoidal dose response model). Each extract concentration was tested in triplicate and experiments were repeated twice.