Table 5. Frequencies of atypical amino acids in HBV/E isolates from different African countries.
| Frequency in isolates from | ||||
| Amino acid/Position | Protein | Angola, Namibia and DRCa | Other African countriesb | P value |
| Ile57 | Small S | 27/28 (96%) | 12/185 (6%) | <0.0001 |
| His177 | Polymerase | 22/28 (79%) | 0/185 (0%) | <0.0001 |
| Trp245 | Polymerase | 22/28 (79%) | 13/185 (7%) | <0.0001 |
| Leu612 | Polymerase | 24/28 (86%) | 22/185 (12%) | <0.0001 |
| Leu30 | X | 24/28 (86%) | 1/185 (1%) | <0.0001 |
a
Democratic Republic of Congo.
b
Cameroon, Central African Republic, Côte d'Ivoire, Ghana, Guinea, Madagascar, Niger, Nigeria and Sudan.