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. 2014 Mar 14;9(3):e92224. doi: 10.1371/journal.pone.0092224

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© 2014 Dazzi et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Dopaminergic neurons show a typical I_h current when the membrane is hyperpolarized starting from −100 mV. (B) Representative traces of spontaneous AP firing recorded from single VTA dopaminergic neuron from fed ad libitum and FR rats (sacrificed 5 min before food consumption). (C) Bar graph representing the quantitative effect of FR on spontaneous AP firing recorded in VTA dopaminergic neurons. ^a P<0.0001 vs rats fed ad libitum, unpaired t-Test. Data are calculated from 8 animals, including 16 cells from rats fed ad libitum, and 18 cells from FR animals. (D) Bar graph representing the resting membrane potential of VTA dopaminergic neurons, for the indicated numbers of cells, from fed ad libitum and FR rats. ^a P<0.05 versus fed ad libitum, unpaired t-Test.