Table 1. The control subjects' and the patient's mean FA values of different ROIs as calculated from DTI. Significance levels (* p<0.05, ** p<0.001, *** p<0.0001).
ROI FA values | Controls | Patient | ||||||||
DTI | DTI-1 | DTI-2 | DTI-3 | DTI-4 | ||||||
Mean | SD | Mean | % reduction relative to controls | Mean | % change relative to DTI-1 | Mean | % change relative to DTI-2 | Mean | % change relative to DTI-3 | |
FA whole WM | 0.355 | 0.020 | 0.223 | −37 (**) | 0.203 | −9 | 0.188 | −7 | 0.171 | −9 |
FA occipital lobe | 0.309 | 0.020 | 0.143 | −54 (***) | 0.122 | −14 | 0.126 | 3 | 0.121 | −4 |
FA parietal lobe | 0.340 | 0.021 | 0.166 | −51 (***) | 0.148 | −11 | 0.142 | −4 | 0.136 | −4 |
FA frontal lobe | 0.346 | 0.025 | 0.203 | −41 (**) | 0.177 | −13 | 0.163 | −8 | 0.139 | −15 |
FA corpus callosum | 0.445 | 0.036 | 0.247 | −45 (**) | 0.216 | −12 | 0.195 | −10 | 0.175 | −10 |
FA corona radiata | 0.357 | 0.023 | 0.199 | −44 (**) | 0.175 | −12 | 0.157 | −10 | 0.141 | −10 |
FA corticospinal tract | 0.389 | 0.022 | 0.263 | −32 (**) | 0.242 | −8 | 0.218 | −10 | 0.202 | −7 |
FA internal capsule | 0.420 | 0.024 | 0.325 | −23 (*) | 0.303 | −7 | 0.278 | −8 | 0.260 | −6 |
FA brain stem | 0.395 | 0.020 | 0.337 | −15 (*) | 0.324 | −4 | 0.305 | −6 | 0.284 | −7 |
FA temporal lobe left | 0.351 | 0.018 | 0.214 | −39 (***) | 0.204 | −4 | 0.189 | −7 | 0.181 | −4 |
FA temporal lobe right | 0.348 | 0.021 | 0.226 | −35 (**) | 0.209 | −7 | 0.202 | −4 | 0.196 | −3 |