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. Author manuscript; available in PMC: 2015 Mar 13.
Published in final edited form as: J Med Chem. 2013 Nov 6;57(5):1952–1963. doi: 10.1021/jm401362f

Figure 2.

Figure 2

IFD pose of the designed 6-aminoquinolone 8(green) overlaid with the X-ray conformation of the known quinolone TSII-NNI 1 (magenta). Key NS5B residues are represented as sticks, whereas hydrogen bonds are represented as yellow dashed lines.