Table 1.
Patient characteristics
| Esophagectomy (n=1204) | Local Therapy (n=254) | p-value | |
|---|---|---|---|
|
| |||
| Age (mean, SD), years | 64.4 (10.0) | 73.4 (9.7) | <0.001 |
|
| |||
| Female | 190 (15.8%) | 60 (23.6%) | 0.003 |
|
| |||
| Race | |||
| White | 1,111 (92.3%) | 240 (94.5%) | 0.17 |
| Black | 45 (3.7%) | 10 (3.9%) | |
| Other/Unknown | 48 (4.0%) | 4 (1.6%) | |
|
| |||
| Marital Status | |||
| Married | 850 (70.6%) | 164 (64.6%) | 0.06 |
| Other/Unknown | 354 (29.4%) | 90 (35.4%) | |
|
| |||
| Tumor location | |||
| Mid esophagus | 199 (16.5%) | 56 (22.1%) | 0.04 |
| Lower esophagus | 1,005 (83.5%) | 198 (78.0%) | |
|
| |||
| Tumor grade | |||
| G1/2 (well/moderate) | 649 (53.9%) | 105 (41.3%) | <0.001 |
| G3/4 (poor/undifferentiated) | 342 (28.4%) | 41 (16.1%) | |
| Unknown | 213 (17.7%) | 108 (42.5%) | |
|
| |||
| Histology | |||
| Squamous cell carcinoma | 220 (18.3%) | 38 (15.0%) | 0.21 |
| Adenocarcinoma | 984 (81.7%) | 216 (85.0%) | |
|
| |||
| Radiation therapy | |||
| No radiotherapy | 957 (79.5%) | 217 (85.4%) | 0.02 |
| Beam radiotherapy | 242 (20.1%) | 34 (13.4%) | |
| Unknown | 5 (0.4%) | 3 (1.2%) | |
|
| |||
| Cause of death | |||
| Alive | 831 (69.0%) | 179 (70.5%) | <0.001 |
| Esophagus | 228 (18.9%) | 27 (10.6%) | |
| Other cause of death | 145 (12.0%) | 48 (18.9%) | |
|
| |||
| Time period | |||
| Early (1998–2003) | 487 (40.4%) | 48 (18.9%) | <0.001 |
| Late (2004–2008) | 717 (59.6%) | 206 (81.1%) | |