Table 2.
Comparison of calpain-1-null with WT erythrocytes
Values are means+S.E.M. (n =6). MCHC, mean corpuscular haemoglobin concentration. Total intracellular ion concentration, mmol/kg of haemoglobin.
| Parameter | WT erythrocytes | Calpain-1-null erythrocytes | P value |
|---|---|---|---|
| MCV (fl) | 47.20±0.92 | 49.50±0.48 | 0.0298 |
| Haematocrit (%) | 35.88±1.56 | 42.90± 3.06 | 0.0390 |
| Haemoglobin (g/dl) | 11.28±0.39 | 13.58± 0.89 | 0.0252 |
| MCHC (%) | 32.44±0.43 | 31.80± 0.35 | 0.1398 |
| [Na+ ]i | 4.58±0.11 | 3.48± 0.16 | 0.0002 |
| [K+ ]i | 123.80±4.12 | 116.22± 5.01 | 0.1350 |
| [Mg2+ ]i | 8.05±0.14 | 8.92± 0.21 | 0.0027 |