Table 1.
The prevalence of the common ZNF750, RAPTOR and TRAF3IP2 variant genotypes
| Gene | SNP | Genotype | Cases | Controls | OR | 95 % CI | p |
|---|---|---|---|---|---|---|---|
| RAPTOR | rs869190 | GG | 311 (60.15 %) | 296 (57.36 %) | – | – | – |
| GT | 169 (32.68 %) | 168 (32.55 %) | 0.961 | 0.553–1.671 | 0.890 | ||
| TT | 28 (5.41 %) | 24 (4.65 %) | 1.288 | 0.424–3.906 | 0.654 | ||
| rs11658698 | CC | 249 (48.16 %) | 256 (49.61 %) | – | – | – | |
| CT | 223 (43.13 %) | 198 (38.37 %) | 1.204 | 0.887–1.635 | 0.233 | ||
| TT | 40 (7.70 %) | 49 (9.40 %) | 0.899 | 0.522–1.549 | 0.701 | ||
| rs12602885 | GG | 328 (63.40 %) | 314 (60.80 %) | – | – | – | |
| AG | 164 (31.70 %) | 165 (31.90 %) | 0.961 | 0.549–1.680 | 0.889 | ||
| AA | 22 (4.25 %) | 21 (4.06 %) | 1.040 | 0.314–3.440 | 0.948 | ||
| ZNF750 | rs8074277 | TT | 287 (55.50 %) | 291 (56.39 %) | – | – | – |
| CT | 201 (38.80 %) | 184 (35.65 %) | 1.083 | 0.061–19.008 | 0.956 | ||
| CC | 24 (4.60 %) | 30 (5.80 %) | NA | NA (0 to infinity) | NA | ||
| rs11077947 | AA | 120 (23.20 %) | 132 (25.60 %) | – | – | – | |
| AG | 260 (50.20 %) | 245 (47.48 %) | 0.993 | 0.670–1.473 | 0.975 | ||
| GG | 134 (25.90 %) | 118 (22.80 %) | 1.093 | 0.672–1.776 | 0.719 | ||
| rs12450046 | GG | 284 (54.90 %) | 284 (55.03 %) | – | – | – | |
| AG | 198 (38.29 %) | 179 (34.68 %) | 0.8860 | 0.051–15.241 | 0.933 | ||
| AA | 24 (4.60 %) | 30 (5.80 %) | NA | NA (0 to infinity) | NA | ||
| TRAF3IP2 | rs13190932 | GG | 408 (78.90 %) | 430 (83.30 %) | – | – | – |
| AG | 93 (17.98 %) | 60 (11.60 %) | 1.107 | 0.158–7.724 | 0.918 | ||
| AA | 10 (1.90 %) | 2 (0.38 %) | NA | NA (0 to infinity) | NA | ||
| rs13196377 | GG | 407 (78.70 % | 432 (83.70 %) | – | – | – | |
| AG | 86 (16.60 %) | 58 (11.24 %) | 0.451 | 0.073–2.767 | 0.389 | ||
| AA | 10 (1.90 %) | 2 (0.38 %) | NA | NA (0 to infinity) | NA | ||
| rs13210247 | AA | 400 (77.36 %) | 427 (82.75 %) | – | – | – | |
| AG | 100 (19.30 %) | 64 (12.40 %) | 1.488 | 0.603–3.670 | 0.388 | ||
| GG | 10 (1.90 %) | 2 (0.38 %) | 2.957 | 0.099–87.863 | 0.531 | ||
| rs33980500 | CC | 378 (73.11 %) | 417 (80.80 %) | – | – | – | |
| CT | 116 (22.40 %) | 69 (13.40 %) | 2.355 | 1.074–5.166 | 0.032* | ||
| TT | 11 (2.12 %) | 3 (0.60 %) | NA | NA (0 to infinity) | NA |
Asterisk indicates statistically significant (p < 0.05)