Table 2.
Summary statistics of lesion imaging parameters (SUVmean, SUVmax and volume) with reproducibility and response 1–2 weeks after RT initiation. Values are presented as mean ± SD. For the reproducibility cohort, 7 primaries and 11 nodes are averaged. For the response cohort, 12 primaries and 18 nodes are averaged
| Lesion | Reproducibility cohort | Response cohort | Test-retest differences (%)b | Responses (%) | ||
|---|---|---|---|---|---|---|
| 1st baseline values | 2nd baseline values | Baseline valuesa | Response values | |||
| Volume (cm3) | ||||||
| Primaries | 38 ± 31 | 40 ± 31 | 78 ± 56 | 85 ± 63 | 9.5 ± 12.8 (9.8) | 6.0 ± 19.1 |
| Nodes | 7.5 ± 4.0 | 8.6 ± 6.3 | 7.4 ± 5.3 | 5.9 ± 5.5 | 8.4 ± 22.5 (19.3) | −16.9 ± 57.0 |
| All | 19 ± 24 | 21 ± 25 | 36 ± 49 | 38 ± 56 | 8.8 ± 18.9 (15.6) | −7.7 ± 46.7 |
| SUVmean | ||||||
| Primaries | 1.6 ± 0.7 | 1.6 ± 0.6 | 2.2 ± 0.7 | 1.6 ± 0.4 | −2.9 ± 8.9 (6.8) | −24.3 ± 13.9 |
| Nodes | 2.1 ± 0.5 | 2.2 ± 0.7 | 1.7 ± 0.4 | 1.1 ± 0.4 | 0.6 ± 18.0 (11.9) | −39.7 ± 14.6 |
| All | 1.9 ± 0.6 | 1.9 ± 0.7 | 1.9 ± 0.6 | 1.3 ± 0.5 | −0.8 ± 14.9 (9.9) | −33.5 ± 16.0 |
| SUVmax | ||||||
| Primaries | 3.5 ± 1.7 | 3.6 ± 1.5 | 5.3 ± 2.0 | 4.1 ± 1.4 | 5.7 ± 12.6 (9.5) | −22.9 ± 13.6 |
| Nodes | 4.0 ± 1.3 | 4.3 ± 1.9 | 3.2 ± 0.9 | 1.8 ± 0.7 | 3.1 ± 17.2 (14.0) | −44.4 ± 15.9 |
| All | 3.8 ± 1.5 | 4.1 ± 1.8 | 4.1 ± 1.7 | 2.7 ± 1.5 | 4.1 ± 15.3 (12.3) | −35.8 ± 18.2 |
aThe second baseline scan was used for patients with two baseline scans
bReproducibility given by the SD of the mean test-retest differences. Average of the individual absolute test-retest differences added in parentheses. Both estimates and mean responses highlighted in bold