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Evaluation of oxidative stress in lung tissue. (A) Levels of malondialdehyde, the end product of lipid peroxidation. (B) Levels of 8-OHdG, a marker of free radicals-induced DNA damage. (C) Activity of manganese superoxide dismutase (MnSOD), an enzyme rapidly inactivated by free radicals. Values are means ± SEM. ###P < 0.001 versus Naive; **P < 0.01 and ***P < 0.001 versus Vehicle.
