Table 1. Treatment Groups for HCT116 +/+ and HCT116 −/− Tumor–Bearing Mice.
| Group | Injection |
|---|---|
| 1 | Intraperitoneal: 150 μL of saline |
| 2 | Intraperitoneal: cisplatin (5 mg/kg) in 150 μL of saline |
| 3 | Intravenous: 22.2 MBq (600 μCi) of 64Cu-DOTA-cetuximab in 150 μL of saline |
| 4 | Intraperitoneal: cisplatin (5 mg/kg) in 150 μL of saline, followed by intravenous injection of 22.2 MBq (600 μCi) of 64Cu-DOTA-cetuximab in 150 μL of saline after 24 h |
| 5 | Intravenous: 50 μg of cetuximab in 150 μL of saline |
| 6 | Intraperitoneal: cisplatin (5 mg/kg) in 150 μL of saline, followed by intravenous injection of 50 μg of cetuximab in 150 μL of saline after 24 h |
| 7 | Intravenous: 22.2 MBq (600 μCi) of 64Cu-IgG in 150 μL of saline |
Mice received 2 treatments 1 wk apart for each group.