Table 1.
| ||||
---|---|---|---|---|
Entry | Solvent | Catalyst (2 mol%) | k (hr−1)a | τ1/2 (h) |
1b | 1,2-DCE | None | 0.0105 (3) | 66 |
2b | 1,2-DCE | Pd(PhCN)2Cl2 | 0.181 (4) | 3.8 |
3c | MeOH | None | 0.0022 (1) | 315 |
4c | MeOH | [Rh(L)]BF4 | 0.072 (5) | 9.6 |
5c | 9:1 tol:DCM | None | 0.0870 (2) | 8.0 |
6c | 9:1 tol:DCM | [Rh(L)]BF4 | 0.0949(5) | 7.3 |
Rate constant for racemization, see Reist et al.26 for definitions. All rate constants are mean values of 3 kinetic runs. Values in parenthesis are sample standard deviations in the final decimal place.
Measured by the polarimetry method.
Measured by the SFC method. L = COD + (S,S)-Ph-BPE