Table 3.
Cross-Section Estimates: Impact of Celera’s IP on Innovation Outcomes
| (1) | (2) | (3) | |
|---|---|---|---|
| Panel A: publications in 2001–2009 | |||
| mean = 2.197 | |||
| celera | −0.877 (0.177)*** | −0.328 (0.099)*** | −0.264 (0.107)*** |
|
| |||
| Panel B: 1(known, uncertain phenotype) | |||
| mean = 0.453 | |||
| celera | −0.162 (0.015)*** | −0.158 (0.015)*** | −0.128 (0.017)*** |
|
| |||
| Panel C: 1(known, certain phenotype) | |||
| mean = 0.081 | |||
| celera | −0.027 (0.007)*** | −0.017 (0.006)*** | −0.014 (0.007)** |
|
| |||
| Panel D: 1(used in any diagnostic test) | |||
| mean = 0.060 | |||
| celera | −0.023 (0.006)*** | −0.014 (0.005)*** | −0.013 (0.006)** |
|
| |||
| indicator variables for year of disclosure | yes | yes | yes |
| number of publications in each year 1970–2000 | no | yes | yes |
| detailed cytogenetic & molecular covariates | no | no | yes |
|
| |||
| N | 27,882 | 27,882 | 16,485 |
Notes: Gene-level observations. All estimates are from ordinary-least-squares (OLS) models. Samples in Columns (1) and (2) include all genes; sample in Column (3) includes all genes with non-missing cytogenetic and molecular covariates. Robust standard errors shown in parentheses.
p< 0.10;
p< 0.05;
p< 0.01.
“Celera”: 0/1, =1 for a Celera gene. Indicator variables for year of disclosure: 0/1 indicator variables for the year sequence for the gene was disclosed. Number of publications in each year 1970–2000: count variables for the number of publications on each gene in each year from 1970 to 2000. Detailed cytogenetic & molecular covariates: 0/1 indicator variables for the chromosome (1–22, X, or Y) and arm (p or q) on which a gene is located; continuous variables for region, band, subband, start base pair, and end base pair; and 0/1 indicator variables for the orientation of the gene on the genome assembly (plus or minus). See text and the online appendix for more detailed data and variable descriptions.