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Mixed leukocyte accumulation induced by eotaxin in ALOX and PAS mice. 5-LO-deficient mutant (ALOX) and wild-type (WT) control PAS mice were injected with RPMI (open bars) or eotaxin, 50 ng/cavity (black bars). The peritoneal lavage fluid collected after 4 h was used for quantitation of total leukocytes (a), eosinophils (b), macrophages (c), and neutrophils (d). Data are mean + SEM. *, P ≤ 0,05; **, P ≤ 0,01. Data from 10 experiments.
