Table 2.
Changes of volume, mean, and geometric mean diameter of the largest myoma per patient during the treatment. Median and interquartile range (IQR) are shown for the volume parameters for which normal distribution was rejected, and mean ± SD is shown for the diameter parameters for which normal distribution was not rejected. P values for intergroup comparison by Mann-Whitney U test.
| Group | iCR | Tibolone | P |
|---|---|---|---|
| N | 34 | 28 | |
| Volume (mm³) | |||
| Visit 1 | 1787 (559; 6107) | 1063 (520; 8060) | 0.35 |
| Visit 3 | 1086 (0; 5991) | 1096 (448; 4695) | 0.91 |
| Volume change (%) | −30.3 (−100.0; +12.7) | +4.7 (−35.9; +88.3) | 0.016 |
| Mean diameter (mm) | |||
| Visit 1 | 18.7 ± 10.6 | 16.5 ± 10.7 | 0.37 |
| Visit 3 | 15.1 ± 12.8 | 14.8 ± 8.5 | 0.85 |
| Mean diameter change (%) | −25.6 ± 47.6 | +6.6 ± 54.7 | 0.021 |
| Geometric mean diameter (mm) | |||
| Visit 1 | 18.6 ± 10.5 | 16.0 ± 9.2 | 0.35 |
| Visit 3 | 14.8 ± 12.9 | 14.4 ± 8.9 | 0.91 |
| Geometric mean diameter Change (%) | −26.6 ± 48.8 | +6.1 ± 58.0 | 0.016 |