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Change in serum uric acid (UA) with allopurinol, benzbromarone, or both drugs.
| Parameter | Allopurinol | Benzbromarone | Both drugs | P |
|---|---|---|---|---|
| Age (years) | 58.5 ± 10 | 45.7 ± 8.3 | 57.8 ± 11.8 | 0.093 |
| Urine UA (mg/day) | 575 ± 397 | 595.5 ± 466 | 461.8 ± 251.5 | 0.857 |
| Pretreatment serum UA (mg/dL) | 9 ± 1.6 | 9.1 ± 1 | 8.2 ± 1.4 | 0.499 |
| Posttreatment serum UA (mg/dL) | 6.7 ± 1.5 | 5.1 ± 1.6 | 4.6 ± 2.3 | 0.01* |
*Serum UA posttreatment with allopurinol versus serum UA posttreatment with benzbromarone or both drugs.
