Table 3.
Laboratory and clinical variables before and after 28-day treatments in the two groups.
| Variables | Groups | Baseline | Day 14 | Day 28 | Delta | P a Value |
|---|---|---|---|---|---|---|
| TB (μmol/L) | Fistuloclysis | 38.2 ± 9.8 | 26.2 ± 8.5 | 18.1 ± 6.2 | 20.3 ± 9.7 | <0.001* |
| Control | 40.7 ± 11.2 | 35.8 ± 10.6 | 24.8 ± 7.1 | 15.6 ± 6.3 | 0.013* | |
| P b | 0.243 | 0.040* | ||||
| DB (μmol/L) | Fistuloclysis | 19.6 ± 8.5 | 12.6 ± 5.8 | 7.2 ± 2.3 | 12.5 ± 3.4 | <0.001* |
| Control | 21.4 ± 10.0 | 18.2 ± 7.5 | 11.3 ± 3.5 | 10.0 ± 3.6 | 0.012* | |
| P b | 0.139 | 0.011* | ||||
| IB (μmol/L) | Fistuloclysis | 18.3 ± 6.6 | 13.2 ± 4.3 | 12.6 ± 3.6 | 5.7 ± 2.0 | 0.026* |
| Control | 19.1 ± 7.1 | 17.7 ± 5.6 | 13.2 ± 4.4 | 5.9 ± 1.5 | 0.043* | |
| P b | 0.183 | 0.285 | ||||
| ALT (U/L) | Fistuloclysis | 55.6 ± 20.7 | 56.4 ± 22.3 | 48.1 ± 16.5 | 7.3 ± 3.1 | 0.025* |
| Control | 50.5 ± 17.6 | 62.5 ± 25.1 | 53.6 ± 15.7 | 3.2 ± 1.2 | 0.181 | |
| P b | 0.058 | 0.033* | ||||
| ALP (U/L) | Fistuloclysis | 212.2 ± 85.1 | 165.1 ± 65.2 | 113.7 ± 41.3 | 98.4 ± 33.5 | <0.001* |
| Control | 219.7 ± 89.9 | 188.3 ± 69.5 | 161.2 ± 34.7 | 57.6 ± 20.9 | 0.005* | |
| P b | 0.182 | <0.001* | ||||
| GGT (U/L) | Fistuloclysis | 210.9 ± 90.1 | 106.2 ± 44.7 | 53.4 ± 23.9 | 157.5 ± 52.6 | <0.001* |
| Control | 223.4 ± 62.4 | 177.2 ± 70.3 | 103.7 ± 37.5 | 119.8 ± 38.5 | <0.001* | |
| P b | 0.422 | 0.019* | ||||
| TP (g/L) | Fistuloclysis | 56.7 ± 16.6 | 65.2 ± 17.3 | 78.5 ± 25.1 | 21.8 ± 8.7 | <0.001* |
| Control | 58.9 ± 11.8 | 62.1 ± 27.3 | 69.7 ± 28.4 | 10.7 ± 2.1 | 0.032* | |
| P b | 0.763 | <0.001* | ||||
| Alb (g/L) | Fistuloclysis | 31.2 ± 3.4 | 37.1 ± 9.5 | 42.5 ± 12.7 | 11.3 ± 2.5 | <0.001* |
| Control | 32.5 ± 12.8 | 33.4 ± 10.5 | 36.8 ± 7.6 | 4.2 ± 1.3 | 0.078 | |
| P b | 0.472 | <0.001* | ||||
| WBC (109/L) | Fistuloclysis | 11.1 ± 4.0 | 10.3 ± 3.7 | 8.4 ± 2.2 | 2.6 ± 0.9 | 0.418 |
| Control | 10.9 ± 3.9 | 10.1 ± 3.2 | 9.3 ± 2.4 | 1.8 ± 0.4 | 0.068 | |
| P b | 0.304 | 0.061 | ||||
| CRP (mg/L) | Fistuloclysis | 12.6 ± 3.5 | 14.4 ± 6.1 | 10.1 ± 3.7 | 2.3 ± 1.1 | 0.073 |
| Control | 15.2 ± 3.8 | 12.4 ± 4.9 | 13.8 ± 4.2 | 1.5 ± 0.5 | 0.081 | |
| P b | 0.004* | 0.032* | ||||
| Fistula output (mL/day) | Fistuloclysis | 1306.2 ± 281.1 | 753.0 ± 254.5 | 519.6 ± 173.2 | 786.6 ± 285.8 | <0.001* |
| Control | 1455.2 ± 203.6 | 1020.5 ± 312.3 | 1063.7 ± 423.4 | 391.5 ± 125.3 | 0.052 | |
| P b | 0.152 | <0.001* |
TB: total bilirubin; DB: direct bilirubin; IB: indirect bilirubin; ALT: alanine aminotransferase; ALP: alkaline phosphatase; GGT: γ-glutamyltransferase; TP: total protein; Alb: albumin; WBC: white blood cells; CRP: C-reactive protein. Delta value was defined as the changes from baseline to day 28 for each variable. P a indicated the time-dependent changes of variables within groups. P b indicated comparisons between the fistuloclysis group and the control group (for the baseline value and the delta values, resp.). Data were presented as mean ± SD. P value < 0.05 was deemed significant.