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Effect of cardiovascular medications on in vitro ROCK activity in human leukocytes. Representative immunoblotting and density plot of Rho kinase activity in human leukocytes (expressed as p-MBS/t-MBS ratio) under the treatment of pharmaceutical agents as indicated. LPA was used as positive control for Rho kinase activation. *: P < 0.05 versus vehicle. #: P < 0.05 versus LPA. LPA: lysophosphatidic acid.
