Table 2.
Angiogenesis-related genes upregulated in resistant/bevacizumab tumors compared to parental/bevacizumab tumors.
| S.No. | Entrez Gene Name | J5-score | Accession # |
|---|---|---|---|
| 1 | Insulin-like growth factor binding protein 6 (IGFBP6) | 27.040 | NM_002178.2 |
| 2 | Frizzled homolog 4 (Droshophila) (FZD4) | 18.239 | NM_012193.2 |
| 3 | Chemokine (C-X3-C motif) ligand 1 (CX3CL1) | 13.329 | NM_002996.3 |
| 4 | Chemokine (C-X-C motif) receptor 7 (CXCR7) | 13.142 | NM_020311.1 |
| 5 | Phospholipase C, gamma 2 (phosphatidylinositol-specific) (PLCG2) | 12.871 | NM_002661.1 |
| 6 | Biglycan (BGN) | 12.165 | NM_001711.3 |
| 7 | Growth factor receptor-bound protein 10(GRB10) | 11.518 | NM_005311.3 |
| 8 | Chemokine (C-C motif) ligand 5(CCL5) | 10.718 | NM_002985.2 |
| 9 | Fibroblast growth factor 2 (basic) (FGF2) | 9.741 | NM_002006.3 |
| 10 | Caspase 1, apoptosis-related cysteine peptidase (CASP1) | 9.477 | NM_033292.2 |
| 11 | Insulin receptor substrate 1 (IRS1) | 8.817 | NM_005544.1 |
| 12 | Fibroblast growth factor receptor 3(FGFR3) | 8.424 | NM_000142.2 |