Table 3.
Results of β1 and β2 Adrenergic Receptor mediated signaling following a burn injury, without and with β-blockade
| Cardiac Effects |
Metabolism | Muscle Protein |
Fat Metabolism | |
|---|---|---|---|---|
| Burn Injury | -Increased HR -Increased hyperdynamic circulation |
Increased REE |
Degradation increased Synthesis decreased Decreased LBM |
Increased lipolysis Increased circulating TGs, FFAs Increased hepatic steatosis |
| -Increased cardiac work |
||||
| Burn + Propranolol |
||||
| -Decreased HR -Decreased hyperdynamic circulation |
Decreased REE |
Degradation decreased Synthesis increased Increased LBM |
Decreased lipolysis Decreased circulating TGs, FFAs Decreased hepatic steatosis |
|
| -Decreased cardiac work |