Table 6.

miRNAs aberrantly expressed in medullary thyroid cancers (MTCs)

miRNA	Specimen type	Detecting technique	Experimental group	Control group	Expression profile	Reference
miR-323, -370, -129, -137, -10a, -124a, -224, -127, -9, -154	Snap-frozen tissue	RT-PCR	Tumor tissue	Normal thyroid tissue	Up	Nikiforova et al., 2008
miR-183, -375	Snap-frozen tissue	qPCR	SMTC	HMTC	Up	Abraham et al., 2011
miR-9*	Snap-frozen tissue	qPCR	SMTC	HMTC	Down	Abraham et al., 2011
miR-21, -127, -154, -224, -323, -370, -9*, -183, -375	Snap-frozen tissue	qRT-PCR	MTC	Normal thyroid tissue	Up	Mian et al., 2012

HMTC: hereditary medullary thyroid cancer; SMTC: sporadic medullary thyroid cancer