Table 2.
Allele and genotype frequencies of five SNPs in 366 autism trios
| Gene | SNP | Allele and genotype frequency*
|
|
| Patient | Parent | ||
| ZNF533 | rs11885327 | ||
| T | 423 (57.8%) | 806 (55.1%) | |
| C | 309 (42.2%) | 658 (44.9%) | |
| TT | 122 (33.3%) | 226 (30.9%) | |
| TC | 179 (48.9%) | 354 (48.4%) | |
| CC | 65 (17.8%) | 152 (20.8%) | |
| rs1964081 | |||
| A | 320 (43.7%) | 679 (46.4%) | |
| G | 412 (56.3%) | 785 (53.6%) | |
| AA | 65 (17.8%) | 161 (22.0%) | |
| AG | 190 (51.9%) | 357 (48.8%) | |
| GG | 111 (30.3%) | 214 (29.2%) | |
|
| |||
| DOCK4 | rs2217262 | ||
| A | 686 (93.7%) | 1349 (92.1%) | |
| C | 46 (6.3%) | 115 (7.9%) | |
| AA | 323 (88.3%) | 625 (85.4%) | |
| AC | 40 (10.9%) | 99 (13.5%) | |
| CC | 3 (0.8%) | 8 (1.1%) | |
|
| |||
| IMMP2L | rs1528039 | ||
| A | 621 (84.8%) | 1251 (85.5%) | |
| G | 111 (15.2%) | 213 (14.5%) | |
| AA | 262 (71.6%) | 533 (72.8%) | |
| AG | 97 (26.5%) | 185 (25.3%) | |
| GG | 7 (1.9%) | 14 (1.9%) | |
| rs12537269 | |||
| A | 111 (15.2%) | 213 (14.5%) | |
| G | 621 (84.8%) | 1251 (85.5%) | |
| AA | 7 (1.9%) | 12 (1.6%) | |
| AG | 97 (26.5%) | 189 (25.8%) | |
| GG | 262 (71.6%) | 531 (72.5%) | |
*
Data are expressed as number (percentage)