Table 1.
Baseline Characteristics and Current Anti-Osteoporosis Medication (AOM)* Use in Women with Incident Fracture (N = 1,075)
| Characteristic | N | n (%) |
P-Value | |
|---|---|---|---|---|
| No Current AOM (n = 888) | Current AOM (n = 187) | |||
| Prior fracture | 392 | 306 (35) | 86 (47) | .003 |
| Age | ||||
| 55–64 | 376 | 327 (37) | 49 (26) | .008 |
| 65–74 | 345 | 284 (32) | 61 (33) | |
| ≥ 75 | 354 | 277 (31) | 77 (41) | |
| Body mass index, kg/m2 | ||||
| <18.5 (underweight) | 22 | 19 (2.3) | 3 (1.7) | .33 |
| 18.5–24.9 (normal) | 391 | 315 (38) | 76 (42) | |
| 25.0–29.9 (overweight) | 351 | 285 (34) | 66 (37) | |
| ≥ 30 (obese) | 247 | 212 (26) | 35 (19) | |
| EQ-5D “No problems” | ||||
| Mobility | 639 | 549 (65) | 90 (52) | .002 |
| Self-care | 967 | 807 (91) | 160 (87) | .07 |
| Activity | 695 | 592 (67) | 103 (56) | .004 |
| Pain or discomfort | 276 | 232 (27) | 44 (24) | .49 |
| Anxiety or depression | 529 | 442 (51) | 87 (47) | .38 |
| Medical Outcomes Study 36-item Short-Form Survey score <50 | ||||
| Physical function | 292 | 226 (26) | 66 (36) | .004 |
| Vitality | 291 | 229 (26) | 62 (35) | .02 |
| Prior use of AOM | 502 | 403 (45) | 99 (53) | .06 |
| Calcium use | 398 | 314 (36) | 84 (46) | .01 |
| Vitamin D use | 403 | 326 (37) | 77 (42) | .24 |
| Current smoker | 97 | 82 (9.3) | 15 (8.1) | .60 |
| Alcohol (≥ 21 drinks/week) | 11 | 10 (1.1) | 1 (0.6) | .70† |
| Diagnosis | ||||
| Osteoporosis | 196 | 140 (17) | 56 (33) | <.001 |
| Osteopenia | 169 | 135 (16) | 34 (20) | |
| Neither | 643 | 563 (67) | 80 (47) | |
| Bone density test done | 666 | 543 (66) | 123 (72) | .11 |
| Number of falls | ||||
| 0 | 526 | 437 (50) | 89 (49) | .95 |
| 1 | 268 | 222 (25) | 46 (25) | |
| ≥2 | 270 | 222 (25) | 48 (26) | |
| Parental fracture | 186 | 150 (19) | 36 (23) | .29 |
| Somewhat or very concerned about osteoporosis | 852 | 691 (79) | 161 (88) | .004 |
| Location | ||||
| Canada or Australia | 123 | 108 (12) | 15 (8.0) | .16 |
| Europe | 454 | 378 (43) | 76 (41) | |
| United States | 498 | 402 (45) | 96 (51) | |
*
Estrogen, selective estrogen receptor modulators, bisphosphonates, calcitonin, parathyroid hormone, and strontium.
†
Fisher exact test used because of small cell values.