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. 2013 Sep;27(9):523–530. doi: 10.1155/2013/180461

TABLE 4.

The International Consensus Diagnostic Criteria for autoimmune pancreatitis

Feature Typical Indeterminate/suggestive
Pancreatic imaging Diffuse enlargement with delayed enhancement without low-density mass, ductal dilation or duct cut-off
ERCP: Long (>1/3 length of the main pancreatic duct) or multiple strictures without marked upstream dilation		 Segmental/focal enlargement with delayed enhancement
ERCP: Segmental/focal narrowing without marked upstream dilation (duct size <5 mm)
IgG4 IgG4 >2 × upper limit of normal value IgG4 1–2 × upper limit of normal value
Histology (Core biopsy/resection): at least 3 features

  1. Periductal lymphoplasmacytic infiltrate without granulocytic infiltration

  2. Obliterative phlebitis

  3. Storiform fibrosis

  4. Abundant (>10 cells/hpf) IgG4-positive cells

 (Core biopsy): any 2 features

  1. Periductal lymphoplasmacytic infiltrate without granulocytic infiltration

  2. Obliterative phlebitis

  3. Storiform fibrosis

  4. Abundant (>10 cells/hpf) IgG4-positive cells
Response to steroids Rapid (<2 weeks) radiological resolution or marked improvement in pancreatic or extrapancreatic manifestations Rapid (<2 weeks) radiological resolution or marked improvement in pancreatic or extrapancreatic manifestations

Adapted from reference 35. ERCP Endoscopic retrograde cholangiopancre-atography; hpf High-power field; Ig Immunoglobulin