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ChIP-seq analyses show that Prep1 competes with Meis1 at the genomic level and decreases the number of Meis1 binding genes. (A) Venn diagram showing the number of Meis1 binding sites in the EV, M cells, and MP cells. (B) Venn diagram showing the overlap between the sites bound by Prep1 in MP cells and the Meis1 sites bound by Meis1 only in M cells. (C) GO analysis of tumor-promoting and -inhibiting genes.
