Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Feb 24;111(10):3769–3774. doi: 10.1073/pnas.1321745111

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Fig. 3. — Reduced RNA editing in genes with low nonsynonymous to synonymous rate ratios (d_N/d_S). (A) Fractions of synonymous and nonsynonymous sites edited in the 50% of genes with low d_N/d_S (median d_N/d_S = 0.055) and the 50% of genes with high d_N/d_S (median d_N/d_S = 0.250). Error bars show one SD. P value is from χ² test. (B) The fraction of nonsynonymous sites edited relative to the fraction of synonymous sites edited (f_n/f_s) increases with d_N/d_S. Each dot represents 5% of all human genes with d_N/d_S estimates. (C) The median nonsynonymous editing level relative to the median synonymous editing level increases with d_N/d_S. Each dot represents 5% of all human genes with edited sites and editing level information. In B and C, ρ and P value are from Spearman’s rank correlation based on the binned data. Error bars in B and C show SDs estimated from 1,000 bootstrap samples.