Table I.
Patient characteristics and response to CRT.
| Characteristics | Training set (n=22) | Testing set (n=21) |
|---|---|---|
| Male/female | 17:5 | 14:7 |
| Age (years) | 72 (41–82) | 60 (44–79) |
| Tumor size (cm) | 3.5 (2.5–9.0) | 4.0 (3.0–10.0) |
| Tumor distance from the anal verge (cm) | 3.0 (0–8.0) | 4.0 (0–7.0) |
| Grade of differentiation | ||
| Well/moderately | 22 | 20 |
| Poorly | 0 | 1 |
| Tumor stage | ||
| T3 | 20 | 19 |
| T4 | 2 | 2 |
| Nodal stage (N) | ||
| 0 | 8 | 11 |
| 1 | 7 | 5 |
| 2 | 7 | 5 |
| Pathological response (grade) | ||
| 0 | 0 | 0 |
| 1 | 7 | 9 |
| 2 | 13 | 11 |
| 3 | 2 | 1 |
| RECIST | ||
| CR | 0 | 0 |
| PR | 14 | 13 |
| SD | 8 | 8 |
| PD | 0 | 0 |
| Downstaging | ||
| Yes | 13 | 11 |
| No | 9 | 10 |
CRT, chemoradiotherapy; RECIST, Response Evaluation Criteria in Solid Tumors; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease.