Table 1.
Baseline characteristics.
| Healthy volunteers (n = 28) |
Patients (n = 18) |
P value | |
|---|---|---|---|
| Age (years) | 25.7 ± 7.1 | 60.6 ± 8.8 | <0.001 |
| Gender (male) | 24 (85.7) | 11 (61.1) | <0.001 |
| Ethnicity (white) | 19 (67.8) | 13 (72.2) | Ns |
| BMI | 23.9 (2.7) | 31.2 (6.6) | <0.001 |
| Systolic BP (mmHg) | 131 (9.1) | 127.3 (17.2) | Ns |
| Diastolic BP (mmHg) | 75.1 (8.3) | 74.4 (11.5) | Ns |
| Hypertension | 0 (0) | 10 (55.5) | <0.001 |
| Diabetes | 0 (0) | 6 (33.3) | <0.001 |
| Current smoker | 0 (0) | 3 (16.7) | <0.001 |
| Concurrent medications: | |||
| Antiplatelet | 0 (0) | 12 (66.7) | <0.001 |
| Statin | 0 (0) | 13 (72.2) | <0.001 |
| Cholesterol (mmol/L) | 4.1 ± 1.0 | 4.2 ± 1.2 | Ns |
| Glucose (mmol/L) | 5.1 ± 0.8 | 6.7 ± 2.5 | Ns |
| Baseline radial artery diameter (mm) | 2.42 ± 0.3 | 2.58 ± 0.4 | Ns |
| Baseline FMD (%) | 7.0 ± 1.9 | 5.4 ± 4.0 | Ns |
Values are mean ± SD or number (%). BMI: body mass index; BP: blood pressure; FMD: flow mediated dilation; Ns: not significant.