Figure 2. Lyophilization and heat stress do not significantly alter the physicochemical characteristics of ID93+GLA-SE.
Particle characterization of liquid and reconstituted lyophilized samples containing ID93 and/or GLA-SE as indicated in the figure labels. (A) Z-Average diameter and (B) polydispersity index from DLS experiments are shown. (C) Zeta potential measurements and (D) particle concentration measurements from nanoparticle tracking analysis are also shown. Filled bars represent unstressed samples (i.e. stored at 4 °C for 30 days) and open bars represent samples stressed at 50°C for 30 days.