Figure 2. R-loop formation, apoptosis, and DNA damage quantitation in ARCAs mouse testes.
A. Percentage of seminiferous tubules containing R-loops. B. Average number of apoptotic spermatocytes per tubule in testes from ARCA mice. C. Percentage of R-loop & TUNEL-positive cells. D. Average number of apoptotic cells containing DNA DSBs (γH2AX). For each panel, 200 tubules were examined per animal and cells were counted in each tubule (n = 3). Error bars represent SEM.