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. 2014 Mar 17;9(3):e90180. doi: 10.1371/journal.pone.0090180

Figure 1. The formation of PEGylated liposomal delivery system of epirubicin and antisense oligonucleotides and particle size distribution of this system.

Figure 1

(A) A schematic diagram for the formation of PEGylated liposomal delivery system containing epirubicin (Epi) combined with antisense oligonucleotides (ASOs) targeting MDR1, MRP1, MRP2, and/or BCL-2/BCL-xL to reverse pump and nonpump resistances, respectively. (B) Particle size distribution of liposomal Epi combined with ASOs targeting MDR1, MRP1, MRP2, and BCL-2/BCL-xL.