Table 1. The percentage of viable MSCs (counted after Tripan Blue staining) after 2, 6, 12, and 18 h of treatment using P. aeruginosa QSSMs.
Viability during time | ||||
---|---|---|---|---|
Experimental condition | 2 h | 6 h | 12 h | 18 h |
MSC controla | 99% | 99% | 100% | 99% |
50 μM OdDHL | 81%* | 63%* | 55%** | 37%*** |
50 μM C4-HSL | 99% | 99% | 93% | 90% |
50 μM PQS | 99% | 94% | 91% | 71%* |
50 μM HHQ | 99% | 99% | 93% | 86%* |
Note: aMSC control contain the same amount of HPLC grade MeOH used for test samples. *P < 0.05, **P < 0.01, ***P < 0.001, based on ANOVA and Bonferroni post test of medians of 3 independent experiments performed in triplicate (n = 3).