Skip to main content
editorial
. 2013 Dec 13;13(3):335–336. doi: 10.4161/cc.27507

graphic file with name cc-13-335-g1.jpg

Figure 1. Induction of hemogenesis in mouse fibroblasts and perspectives. Gata2, cFos, Gfi1b, and Etv6 were identified as sufficient to induce a hemogenic program in mouse fibroblasts. First, endothelial precursor cells are induced that generate semi-adherent cells with hematopoietic stem cell features. Future perspectives are highlighted including translation to the human system and comparison with hematopoietic stem cell specification during embryogenesis.