Table 1.
Demographic and clinical characteristics of patients with vascular dementia randomized to the fluoxetine and control groups
| Characteristic | Fluoxetine group | Control group | P-value |
|---|---|---|---|
| Sex (male/female), n | 13/12 | 14/11 | 0.777 |
| Age (years), mean (SD) | 66.4 (7.7) | 67.8 (9.2) | 0.562 |
| BMI (kg/m2), mean (SD) | 23.3 (1.8) | 23.5 (2.0) | 0.734 |
| Education (years), mean (SD) | 8.6 (4.5) | 9.4 (3.8) | 0.306 |
| MMSE score, mean (SD) | 15.1 (3.0) | 15.7 (2.6) | 0.490 |
| TPC score, mean (SD) | 3.7 (1.2) | 4.1 (1.1) | 0.330 |
| VFT score, mean (SD) | 14.7 (4.5) | 15.7 (4.2) | 0.231 |
| Digit Span score, mean (SD) | 4.6 (1.3) | 4.9 (1.2) | 0.251 |
| BDNF (ng/mL), mean (SD) | 21.2 (3.2) | 21.4 (5.8) | 0.885 |
Abbreviations: BDNF, brain-derived neurotrophic factor; BMI, body mass index; MMSE, Mini-Mental State Examination; n, number of patients; SD, standard deviation; TPC, Ten-Point Clock Drawing; VFT, Verbal Fluency Test.