Figure 5.

Cryo-TEM of ID93–liposomes. Cryo-TEM image of ID93–liposome mixture (0.25 mg/mL ID93, 4 mg/mL phospholipid) reveals many of the same liposome and protein particles present in the individual samples such as spherical unilamellar liposomes (yellow arrow), linear protein particles (light green), and clustered protein particles (orange arrow). Some of the spherical liposome bilayers contained black dots, possibly indicating embedded protein. Other novel structures included pairs of rod-like particles (pink), some of which were decorated by black dots or other proteinaceous structures (light pink), and faint round particles (maroon arrow) which also sometimes appeared decorated with protein (dark green). The sample was imaged at 52,000× magnification. Scale bar =200 nm.

Abbreviation: Cryo-TEM, cryogenic transmission electron microscopy.