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. 2014 Mar 17;9(3):e91351. doi: 10.1371/journal.pone.0091351

Figure 3. Partial sequence chromatograms of the OPHN1 intron (AluJo) isolated from different human tissues (brain, spinal cord, skin).

Figure 3

For each tissue both the gDNA and the corresponding cDNA are shown. Arrows indicate selected edited positions (site 1, 2, 8, 9, 10 and 11) and the corresponding editing levels of the sequence chromatograms are reported above each site as percentages (%). Editing appears as a double peak of adenosine (green) and guanosine (black) in cDNA sequences, whereas only adenosines are present in the gDNA. A representative experiment out of three is shown. Editing levels at all the AluJo editing sites as found in human brain, spinal cord, skin as well as kidney and thyroid are reported in Table 1.