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ARV interactions with substances of abuse
| ARV | Potential interaction with substances of abuse |
|---|---|
| Efavirenz | Enhanced cannabis effect by CYP3A4 inhibition |
| Precipitated methadone withdrawal by CYP3A4 induction | |
| Ritonavir | Enhanced oxycodone effect by CYP2D6 inhibition |
| Enhanced MDMA effect by CYP2D6 inhibition | |
| Enhanced GHB effect by CYP450 inhibition | |
| Nevirapine | Precipitated methadone withdrawal by CYP3A4 induction |
