Table 5.

Outcomes used in clinical trials for Alzheimer’s disease and mild cognitive impairment

Staging	Cognition	ADLs	Global
Mini-Mental State Examination (MMSE)	Alzheimer’s Disease Assessment Scale- cognitive subscale (ADAS-cog)	Alzheimer’s Disease Cooperative Study- Activities of Daily Living (ADCS-ADL)	Alzheimer’s Disease Cooperative Study- Clinical Global Impression of Change (ADCS-CGIC)
Clinical Dementia Rating Scale (CDR)	Neuropsychological Test Battery (NTB)	Disability in Alzheimer’s Disease (DAD)	Clinical Dementia Rating Scale-sum of boxes (CDR-SB)
Global Deterioration Scale (GDS)	Mini-Mental State Examination (MMSE)	Progressive Deterioration Scale (PDS)	Gottfries-Brane-Steen (GBS)
Gottfries-Brane-Steen (GBS)	Severe Impairment Battery (SIB)	Bristol activities of daily living (ADL)