Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Mar 17;9(3):e91709. doi: 10.1371/journal.pone.0091709

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Xu et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Western blot analysis depicting Dab2 expression in SK-BR-3 cells after transfection with pcDNA3.1/Dab2. (B) TGF-β depletion by mock- and Dab2-transfected SK-BR-3 cells were measured with the reporter assay. Re-installation of Dab2 partially restored TGF-β depletion in the SK-BR-3 Dab2 cells, indicated by significant lower TGF-β content in its condition medium compared with the condition medium of SK-BR-3 V cells. (C) Influence of Dab2 on recycling of Tfn in breast cancer SK-BR-3 cells. Bar, 25 um. (D) After endocytosis, Tfn accumulates in the cytoplasm around the nucleus. The proportion of cells that showed diffued staining(indicative of Tfn recycling) within 15 min, out of a total of 50 cells examined, was calculated. *P<0.05.