Table 1.
Tissue-specific regulation by functional characterization.
| NO. | LIVER-SPECIFIC FUNCTIONS* | MUSCLE-SPECIFIC FUNCTIONS* |
|---|---|---|
| 1 | Ribosome (1)$ | Adipocytokine signaling pathway (1) |
| 2 | TGF-beta signaling pathway (3) | Fatty acid metabolism (1) |
| 3 | Ribosome (5) | Glutathione metabolism (1) |
| 4 | Arginine and proline metabolism (6) | Nod-like receptor signaling pathway (1) |
| 5 | Antigen processing and presentation (7) | Pyrimidine metabolism (1) |
| 6 | Cell adhesion molecules (7) | RNA polymerase (1) |
| 7 | Complement and coagulation cascades (7) | B cell receptor signaling pathway (2) |
| 8 | Leukocyte transendothelial migration (7) | Calcium signaling pathway (2) |
| 9 | Systemic lupus erythematosus (7) | DNA replication (2) |
| 10 | Complement and coagulation cascades (11) | ErbB signaling pathway (2) |
| 11 | Drug metabolism—cytochrome P450 (11) | Fc gamma R-mediated phagocytosis (2) |
| 12 | Retinol metabolism (11) | Gap junction (2) |
| 13 | Starch and sucrose metabolism (11) | Glycolysis/Gluconeogenesis (2) |
| 14 | Valine, leucine and isoleucine degradation (11) | GnRH signaling pathway (2) |
| 15 | Long-term potentiation (2) | |
| 16 | Melanogenesis (2) | |
| 17 | Natural killer cell mediated cytotoxicity (2) | |
| 18 | Phosphatidylinositol signaling system (2) | |
| 19 | Pyruvate metabolism (2) | |
| 20 | Regulation of actin cytoskeleton (2) |
Notes:
*
Functions are KEGG pathways that are enriched by sets of coexpressed genes in corresponding expression patterns. (x)$, corresponding expression patterns of functions.